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작성자스템플러 조회 10회 작성일 2022-01-23 19:04:27 댓글 0


Age Expert Answers Aging Questions From Twitter | Tech Support | WIRED

Dr. Morgan Levine, a professor who specializes in the biology of aging, answers the internet's burning questions about aging. Is there anyway to stop aging? Is aging a disease? Do you age slower in space? Dr. Levine answers all these questions and much more!

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Age Expert Answers Aging Questions From Twitter | Tech Support | WIRED
Stunna girl : She's really taking advantage of her degree. Her skin is GLOWING
Klaus Gaming : I think she knows the secret to stop aging, but is keeping it to herself
AllGoodThingsNetwork : I was hoping that someone asked about the leaps in aging we make and I suppose they kind of did. I read years ago that we don't age outwardly day by day, but rather there are these seismic events that age us a lot all at one time. So maybe you cruise through your early 30s and still look 26, but then you get a divorce and suddenly you're aged by 10 years. Based on what I've seen in life, that seems to be true.
Subby : Waiting for her to just be like
"I'm actually 70, please fund my lab"
Midnightstar2675 : I love how she brings the focus on healthspan and living a more comfortable life rather than just trying to extend a painful and degraded state. Rather than trying to extend life, focusing on the health problems with aging makes so much more sense and like she said would probably result in more years anyway. My biggest fears with aging is developing something like Alzheimer’s, it’s really reassuring to remember how hard people are working to ease these issues

This Harvard Professor Explains the Secret to Aging in Reverse | David Sinclair on Health Theory

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A Simple, Timeless Guide to Goal-Setting:

Harvard professor David Sinclair believes that not only can we slow aging down, we can actually reverse it. On this episode of Health Theory with Tom Bilyeu, David Sinclair explains the three levels of aging, and what can be done on each level. He describes the lifestyle changes that slow aging down, the drug treatments that begin to stop aging, and experimental new procedures that may actually reverse aging once they are fully developed.


David explains the information theory of aging [0:59]
David explains the difference between genes and the epigenome [2:17]
David describes the way that cell stress causes aging [5:20]
David explains what proteins are and how they work [6:40]
David recommends lifestyle changes to slow down or reverse aging [9:14]
David recommends stressing the system by consistent fasting [10:52]
David explains why we don’t live as long as whales [15:01]
David describes resetting the biological clock [16:16]
David explains how to tell when someone is going to die [18:47]
David explains why people are taking metformin [20:03]
David shares his regimen of exercise and metformin [24:18]
David advocates cold exposure [25:28]
David explains work he’s done to try to reset the aging clock [29:01]
David explains why you don’t want to turn the cellular clock back too far [31:37]
David describes the actual process of reversing aging in masses of cells [33:20]
David talks about some results with mice that appear to reverse aging [36:40]
David shares his father’s story of metformin and NMN use [38:10]
David explains the effects of resveratrol [39:07]
David describes the kinds of testing he advocates [43:13]
David shares the impact he wants to have on the world [45:44]



IMPACT THEORY MERCHANDISE: Check out Impact Theory's Merch Shop:
Seymor BUTTS : My great grandma passed at 107. She slept often, always had a beer or glass of red wine at dinner. She ate home cooked meals and survived the great depression by begging for bread on the street with her sisters. She also drank lots of water and occasionally had orange juice. She stayed sharp speaking two languages and listening to classical music. She passed away a week after being in a nursing home. My family took better care of her until they just couldn't. They all wish they hadn't sent her. R.i.p. great grandma.
johnpearcey : Tom seems to ask exactly the right questions to aid our understanding of a very complex subject. Excellent interview.
Costas Costas : 13:20 I trust this guy only because of what he said: "nobody knows what is the perfect diet, all I can tell you is for rodents" "what we discovered... what my colleagues discovered..." he knows the limitations of his research and he gives credit where it is due, which means that if he says something I am happy he believes in it and does not hype it up. Trustworthy!
nurhan toguc : Love scientists like Dr. Sinclair who contributes to public health, despite big pharma preventions. Hope we have more of scientists like yourself. Proud of you
René Simon Pfisterer : Guaranteed Agestopper:
1. Eliminate Stress
2. No processed food
3. No industrial refined sugar. Only fruit sugar or natural unprocessed cane sugar or honey in moderate dosis
4. Regular meditation
5. Regular sports
6. Connect with nature without electronic devices regularly
7. Keep your inner child alive
8. Laugh a lot and take life not so serious
9. Connect and hug with the most important people
Your welcome ;)

How to Slow Aging (and even reverse it)

Scientists like Prof Sinclair have evidence of speeding up, slowing, and even reversing aging.
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What causes aging? According to Professor David Sinclair, it is a loss of information in our epigenome, the system of proteins like histones and chemical markers like methylation that turn on and off genes. Epigenetics allow different cell types to perform their specific functions - they are what differentiate a brain cell from a skin cell. Our DNA is constantly getting broken, by cosmic rays, UV radiation, free radicals, x-rays and regular cell division etc. When our cells repair that damage, the epigenome is not perfectly reset. And hence over time, noise accumulates in our epigenome. Our cells no longer perform their functions well.

To counter this decline, we can activate the body's own defenses against aging by stressing the body. Eat less, eat less protein, engage in intense exercise, experience uncomfortable cold. When the body senses existential threats it triggers longevity genes, which attempt to maintain the body to ensure its survival until good times return. This may be the evolutionary legacy of early bacteria, which established these two modes of living (repair and protect vs grow and reproduce). Scientists are uncovering ways to mimic stresses on the body without the discomfort of fasting. Molecules like NMN also trigger sirtuins to monitor and repair the epigenome. This may slow aging.

Reversing aging requires an epigenetic reset, which may be possible using Yamanaka factors. These four factors can revert an adult cell into a pluripotent stem cell. Prof. Sinclair used three of the four factors to reverse aging in the retinal cells of old mice. He found they could see again after the treatment.

Special thanks to:
Professor David Sinclair, check out his book "Lifespan: Why We Age \u0026 Why We Don't Have To"
Assistant Professor David Gold
Noemie Sierra (for polyp images)
Genepool Productions for telomere animations from Immortal:
Epigenetics animations (DNA, histones, methylation etc) courtesy of:
Animation: Etsuko Uno
Art and Technical Direction: Drew Berry
Sound Design: Francois Tetaz \u0026 Emma Bortignon
Scientific Consultation: Marnie Blewitt
Courtesy of Walter and Eliza Hall Institute of Medical Research

Filming, editing and animation by Jonny Hyman and Derek Muller

Music from "Clearer Views" "Innovations" "A Sound Foundation" "Seaweed"
Additional music by Kevin MacLeod from "Marty Gots a Plan"
JustusLM : I think Professor Sinclair will be a key figure in aging research for at least the next 300 years or so.
piosenki001 : It is physically impossible to say "mitochondria" without adding an explanation that its a "powerhouse of a cell".
Daniel Aleksander Jensen : It's all fun and games until you find out that David Sinclair's real age is 150 years.
drageloff : These YouTube tutorials are getting more and more advanced
AAMCO Scott : Professor Sinclair looks like he’s been the subject of his own research.




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